Improved synthesis of substituted 6,7-dihydroxy-4-quinazolineamines: tandutinib, erlotinib and gefitinib.
نویسندگان
چکیده
The synthesis of three substituted 6,7-dihydroxy-4-quinazolineamines: tandutinib (1), erlotinib (2) and gefitinib (3) in improved yields is reported. The intermediates were characterized by NMR and the purities determined by HPLC.
منابع مشابه
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ورودعنوان ژورنال:
- Molecules
دوره 11 4 شماره
صفحات -
تاریخ انتشار 2006